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The Cardiac Autoregulation & Arrhythmias laboratory focuses on the intrinsic regulation of cardiac function and the effects of mechano-electric interactions on heart rhythm. Our goals are to: (i) define organ-to-subcellular autoregulatory mechanisms responsible for (patho-)physiological responses; (ii) discover their relevance for heart rhythm in health and disease; and (iii) apply insights to develop novel targeted anti-arrhythmic therapies.

Our Group

We are exploring a variety of research topics within the fields of cardiovascular physiology and disease. We employ an innovative multi-scale, multi-species approach (in whole animals to isolated tissue and cell preparations from human, rabbit, mouse, and zebrafish), combining advanced engineering-based experimental methods with computational modeling to gain insight into normal and diseased cardiac function at various levels of functional and structural complexity.

Selected Publications